Actress Anne Heche died Friday at 53.

Heche's death comes a week after after she crashed her car into a house in Los Angeles, setting the car and house on fire. Police said she had narcotics in her system.

Heche's family confirmed her death after earlier announcing that she had been taken off life support. She had suffered severe burns and a brain injury in the crash, had been put on a ventilator, and was in a coma.

She was the former partner of Ellen DeGeneres; they were in a relationship from 1997 to 2000 and were a high-profile couple after DeGeneres came out as a lesbian.

Heche later married a man, camera operator Coley Laffoon, and then was in a relationship with James Tupper. She has had one child with each. She authored an autobiography, Call Me Crazy, and talked about being the daughter of a closeted gay man.

Heche’s films included Donnie Brasco, Wag the Dog, John Q, and Gus Van Sant’s remake of Psycho. She appeared in numerous TV series and was Emmy-nominated for one of them, Gracie’s Choice. She won a Daytime Emmy for her role in the soap opera Another World early in her career, and she received GLAAD’s Stephen F. Kolzak Award in 2000, honoring her as an LGBTQ+ media professional who has advanced acceptance of the community.

Recently, she had a recurring role on the TV series All Rise and wrapped a Lifetime movie, Girl in Room 13. She and Heather Duffy had a podcast, Better Together With Anne and Heather.

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